Loading... Please wait...

Diet-induced acidosis: is it real and clinically relevant?-USA

Joseph Pizzorno, Lynda A. Frassetto, and Joseph Katzinger - Bastyr University, Seattle and CTSI - Clinical Research Center - University of California, USA

The concept of diet-induced ‘acidosis’ as a cause of disease has been a subject of interest for more than a century. The present article reviews the
history of our evolving understanding of physiological pH, the physiological support for the concept of ‘acidosis’, the causes of acidosis, how it is
recognised, its short-term effects as well as the long-term clinical relevance of preventative measures, and the research support for normalisation of
pH. Further, we suggest differentiation of the terms ‘acidosis’ and ‘acidaemia’ as a way to resolve the conflation of these topics which has led to
confusion and controversy. The available research makes a compelling case that diet-induced acidosis, not diet-induced acidaemia, is a real
phenomenon, and has a significant, clinical, long-term pathophysiological effect that should be recognised and potentially counterbalanced by
dietary means. ... >> Read more/download pdf